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    Role of mitochondrial functions in drug resistance of tumor cells role of mitochondrial functions in drug resistance of tumor cells Role of mitochondrial functions in drug resistance of tumor cells купить
    Role of mitochondrial functions in drug resistance of tumor cells
    4839 Руб
      Cyclophilin A as an apoptotic effector role of mitochondrial functions in drug resistance of tumor cells Cyclophilin A as an apoptotic effector купить
      Cyclophilin A as an apoptotic effector
      3249 Руб
        A Search for Multi Drug Resistance Modulators role of mitochondrial functions in drug resistance of tumor cells A Search for Multi Drug Resistance Modulators купить
        A Search for Multi Drug Resistance Modulators
        4839 Руб
          ADAM12 in tumor progression role of mitochondrial functions in drug resistance of tumor cells ADAM12 in tumor progression купить
          ADAM12 in tumor progression
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            Assessment of Tumor Thickness and Nodal Dendritic Cells role of mitochondrial functions in drug resistance of tumor cells Assessment of Tumor Thickness and Nodal Dendritic Cells купить
            Assessment of Tumor Thickness and Nodal Dendritic Cells
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              The added value of natural killer cells in immunotherapy for leukemia role of mitochondrial functions in drug resistance of tumor cells The added value of natural killer cells in immunotherapy for leukemia купить
              The added value of natural killer cells in immunotherapy for leukemia
              7790 Руб
                ClC-channels and etoposide resistance role of mitochondrial functions in drug resistance of tumor cells ClC-channels and etoposide resistance купить
                ClC-channels and etoposide resistance
                5290 Руб
                  Stem cells microenvironment and its effects on leukemia treatment role of mitochondrial functions in drug resistance of tumor cells Stem cells microenvironment and its effects on leukemia treatment купить
                  Stem cells microenvironment and its effects on leukemia treatment
                  4139 Руб
                    P-glycoprotein and the development of multidrug resistance role of mitochondrial functions in drug resistance of tumor cells P-glycoprotein and the development of multidrug resistance купить
                    P-glycoprotein and the development of multidrug resistance
                    3249 Руб
                      Breast cancer treatment by targeting breast cancer stem cells role of mitochondrial functions in drug resistance of tumor cells Breast cancer treatment by targeting breast cancer stem cells купить
                      Breast cancer treatment by targeting breast cancer stem cells
                      6690 Руб
                        Expressions of Angiogenic and Apoptotic Markers in Soft Tissue Sarcoma role of mitochondrial functions in drug resistance of tumor cells Expressions of Angiogenic and Apoptotic Markers in Soft Tissue Sarcoma купить
                        Expressions of Angiogenic and Apoptotic Markers in Soft Tissue Sarcoma
                        5790 Руб
                          Non-Genetic Cancer Cell Plasticity role of mitochondrial functions in drug resistance of tumor cells Non-Genetic Cancer Cell Plasticity купить
                          Non-Genetic Cancer Cell Plasticity
                          6890 Руб
                            Gene Cloning and Cancer role of mitochondrial functions in drug resistance of tumor cells Gene Cloning and Cancer купить
                            Gene Cloning and Cancer
                            6390 Руб
                              Role of the AAA protease Yme1 in mitochondrial protein quality control role of mitochondrial functions in drug resistance of tumor cells Role of the AAA protease Yme1 in mitochondrial protein quality control купить
                              Role of the AAA protease Yme1 in mitochondrial protein quality control
                              4429 Руб
                                The role of Indoleamine 2,3 Dioxygenase in Acute Myeloid Leukemia role of mitochondrial functions in drug resistance of tumor cells The role of Indoleamine 2,3 Dioxygenase in Acute Myeloid Leukemia купить
                                The role of Indoleamine 2,3 Dioxygenase in Acute Myeloid Leukemia
                                6690 Руб
                                IDO has a role in immunosuppressive and tolerogenic mechanism in many solid tumor cells. Upregulation of IDO in acute myeloid leukemia has been recently reported. This book presents our research work which assessed both the IDO RNA expression & its enzymatic activity in the blast cells of AML patients. It also assessed the effect of pharmacological IDO inhibitor (1MT) on culture leukemia blast cells in relation to the effect of most traditionally used chemotherapeutic agent: adriamycin. The study included 25 AML patients & 25 healthy volunteers. All underwent assessment of IDO enzymatic activity & IDO RNA estimation by RT-PCR in peripheral blood MNCs. Also the MNCs were cultured to test the effect 1MT alone, and in combination with adriamycin on cell proliferation and IDO expression. The study revealed significant difference of IDO RNA expression & activity among the two groups (p > 0.01). Also there was a significant inhibition of proliferation of blast cells under the effect of both IDO inhibitor & adriamycin (p > 0.01). We concluded that, the role of IDO in tumor induced immune tolerance was confirmed and the benefits effect of IDO inhibitor in enhancing the anticancer effect

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